Use Celigo for 3D Tumor Spheroid-Based Functional Assays – Invasion into Matrigel

Video: 3D tumor spheroid invasion into Matrigel using u-bottom 96-well ULA plates. Examine drug effects on tumor spheroids as a model system for tumor invasion.

By |2021-06-15T17:43:27+00:00October 29th, 2018|Categories: 3D Models, Celigo, Instrument, Video|Tags: , |0 Comments

22nd Annual Merck Technology Symposium

Come visit us at booth #413 Merck Technology Symposium 2018 September 5-6, 2018 Ocean Place Resort Long Branch, NJ Posters being presented: High-throughput foci counting of viral titer and antibody neutralization assays using the Celigo Image Cytometer for developing a novel cross-reactive influenza vaccine Long-term time-course monitoring of NK cell-mediated ADCC using the Celigo Image Cytometer A high-throughput 3D tumor spheroid screening method for drug discovery using imaging cytometry

Automated Cell Counters: Accurate, Reproducible Cell Counts for the Entire Cell Therapy Workflow

Cellometer automated cell counters have been facilitating CAR T manufacturing with accurate cell counting and analysis since 2010.

Celigo Provides Image-Based Proof of Single-Cell Clonality

The FDA identifies clonality as one of the most crucial steps in guaranteeing cell line quality and safety. The Celigo Image Cytometer makes single cell sorting easy.

Poster: High-throughput immune complex analysis method for CAR T cell-mediated cytotoxicity using the Celigo Image Cytometer

Download our Poster Abstract: Cancer immunotherapy has been gaining momentum in the field of cancer research. Specifically, Chimeric Antigen Receptor (CAR) T cell technology have introduced new methods to combat cancer. Direct cell-mediated cytotoxicity assays are required to assess the killing capability of the engineered CAR T cells. Traditionally, these assays are conducted by measuring the amount of released Chromium, calcein AM, or LDH molecules after the target cancer cells are killed with CAR T cells. These methods require a large amount of target cells which may not be ideal when working with donor primary samples. Additionally, they cannot [...]

High throughput, high-resolution image acquisition for DNA damage detection

Celigo playing an important role in high throughput, high-resolution image acquisition for DNA damage detection. The Celigo S captures 16 images of each well that are then stitched into a single representation Open access article: Next generation high throughput DNA damage detection platform for genotoxic compound screening

Celigo Helping Move Research Forward to Find a Cure for Alzheimer’s

November is National Alzheimer's Disease Awareness Month and research into a cure for the disease is vigorous. In a recently published paper "CRISPR/Cas9-Correctable mutation-related molecular andphysiological phenotypes in iPSC-derived Alzheimer’s PSEN2N141I neurons" researchers used the Celigo image cytometer upstream of CRISPR/Cas9 to visualize and asses cell death related to the sensitivity of iPSC-derived PSEN2N1411 neurons in the presence of Aβ42 oligomer toxicity.

By |2021-06-15T19:05:51+00:00November 7th, 2017|Categories: Celigo, Celigo User Publications, Instrument|Tags: , , , |0 Comments

Benefits of direct high-throughput cell counting in immuno-oncology research

By directly imaging and counting every cell in a well over a course of a drug treatment, the Celigo can perform the cytotoxicity assays in a label-free format.

Celigo 5 Channel system officially released

Lawrence, Massachusetts – September, 2016 - Nexcelom Bioscience, a leading provider of cell counting and analysis products for biomedical research and the biopharma industry, announced it has released the addition of a 5th channel available as an option on the Celigo image cytometer. The Celigo is a bench-top image cytometry system providing whole-well imaging and quantitative data, through image analysis for demanding cell-based analytical applications. Previous configurations allowed bright field only imaging, or bright field imaging plus 3 fluorescent channels. This new option of bright field plus 4 fluorescent (red, green, blue and far-red) channels will allow researchers more capabilities [...]

By |2021-06-15T19:09:51+00:00September 8th, 2016|Categories: Celigo, Celigo Application News, Instrument|Tags: |0 Comments
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