Biomarker & Immuno-Oncology World Congress
June 11-13, 2018 | Boston, MA Learn more
Live Webinar: “Patients derived organoids (PDOs) to model therapy response ex vivo”
Join us on Thursday, June 7th for an informational webinar by Somaieh Hedayat of The Institute of Cancer Research. She will discuss different approaches to recapitulate the metastatic niche and compare PDOs drug responses observed in the laboratory ex vivo with clinical responses observed in patients and how those techniques will allow the study of PDO drug responses in the pre-clinical setting strengthening their value as a platform for drug screening, discovery and development. About Somaieh Hedayat: Somaieh Hedayat is working towards a PhD on how the tissue microenvironment can affect the response of metastatic colorectal cancer cells to antiangiogenic therapies. Prior [...]
Poster: High-throughput immune complex analysis method for CAR T cell-mediated cytotoxicity using the Celigo Image Cytometer
Download our Poster Abstract: Cancer immunotherapy has been gaining momentum in the field of cancer research. Specifically, Chimeric Antigen Receptor (CAR) T cell technology have introduced new methods to combat cancer. Direct cell-mediated cytotoxicity assays are required to assess the killing capability of the engineered CAR T cells. Traditionally, these assays are conducted by measuring the amount of released Chromium, calcein AM, or LDH molecules after the target cancer cells are killed with CAR T cells. These methods require a large amount of target cells which may not be ideal when working with donor primary samples. Additionally, they cannot [...]
Nexcelom Bioscience announces strategic growth investment from Ampersand Capital Partners
The latest news from Nexcelom Bioscience March 20, 2018 - Nexcelom Bioscience announces strategic growth investment from Ampersand Capital Partners (PDF) March 20, 2018, Lawrence, MA -- Nexcelom Bioscience, a leading provider of cell counting and analysis products for biomedical research and the biopharma industry, announced today that it has received a strategic investment from Ampersand Capital Partners. The funding will be primarily used to support Nexcelom’s worldwide growth initiatives. Founded in 2003, Nexcelom is a fast-growing supplier of innovative cellular analysis instruments, software and related consumables used in a broad range of research fields including immuno-oncology, cell therapy, drug discovery, [...]
Cellometer and Honey Bees
Cellometer Vision CBA was used to count and determine the viability of collected honey bee sperm.
High throughput, high-resolution image acquisition for DNA damage detection
Celigo playing an important role in high throughput, high-resolution image acquisition for DNA damage detection. The Celigo S captures 16 images of each well that are then stitched into a single representation Open access article: Next generation high throughput DNA damage detection platform for genotoxic compound screening
The Science of Beer
Dr. Chan's paper, "Measuring Lager and Ale Yeast Viability and Vitality Using Fluorescence-Based Image Cytometry" examines the use of image cytometry for multichannel fluorescent assessment of yeast viability and vitality during the brewing process.
Celigo Helping Move Research Forward to Find a Cure for Alzheimer’s
November is National Alzheimer's Disease Awareness Month and research into a cure for the disease is vigorous. In a recently published paper "CRISPR/Cas9-Correctable mutation-related molecular andphysiological phenotypes in iPSC-derived Alzheimer’s PSEN2N141I neurons" researchers used the Celigo image cytometer upstream of CRISPR/Cas9 to visualize and asses cell death related to the sensitivity of iPSC-derived PSEN2N1411 neurons in the presence of Aβ42 oligomer toxicity.
Don’t let clumpy samples prevent you from getting an accurate count!
As the first automated cell counter ever manufactured, the Auto T4 set the standard with its pattern-recognition software and bright field imaging used to calculate cell count, concentration and viability with Trypan Blue.
What do you need when you count cells manually with a microscope and hemacytometer?
...a neck massage! There's a new article out from Biocompare entitled "Cell Counts and More" - and we have to give joke credit to them. We think it's a pretty good one, and accurate, just like our instruments. One of our customers, Tiffany Sidwell, of UCLA Immunogenetics Center, even provided some feedback on the very topic last year. Tiffany shared: "Counting cells daily on the microscope was very bad for my occipital joints and muscles. Since using the Cellometer Auto 2000, I no longer have neck pain when counting cells. Thank you Nexcelom!" There are many, many benefits associated with [...]