Cellometer and Honey Bees

Cellometer Vision CBA was used to count and determine the viability of collected honey bee sperm.

High throughput, high-resolution image acquisition for DNA damage detection

Celigo playing an important role in high throughput, high-resolution image acquisition for DNA damage detection. The Celigo S captures 16 images of each well that are then stitched into a single representation Open access article: Next generation high throughput DNA damage detection platform for genotoxic compound screening

Don’t let clumpy samples prevent you from getting an accurate count!

As the first automated cell counter ever manufactured, the Auto T4 set the standard with its pattern-recognition software and bright field imaging used to calculate cell count, concentration and viability with Trypan Blue. 

What do you need when you count cells manually with a microscope and hemacytometer?

...a neck massage! There's a new article out from Biocompare entitled "Cell Counts and More" - and we have to give joke credit to them. We think it's a pretty good one, and accurate, just like our instruments. One of our customers, Tiffany Sidwell, of UCLA Immunogenetics Center, even provided some feedback on the very topic last year. Tiffany shared: "Counting cells daily on the microscope was very bad for my occipital joints and muscles. Since using the Cellometer Auto 2000, I no longer have neck pain when counting cells. Thank you Nexcelom!" There are many, many benefits associated with [...]

Do you rely on a Flow Cytometer? Want to break free?

If you rely on a flow cytometer in a core lab or a central facilities lab, have you ever wondered if there was a better way? Have you ever wished to have full control over your experiments, rather than hand your sample over to a technician?  There was an interesting article written recently about the needs of researchers. Have you seen this? Those interviewed for the article suggest that there are some main factors for consideration: The instrument size needs a smaller footprint than existing products offer The price of the instrument should be under $100,000 Software ease-of-use to reduce [...]

Having a tough time counting your PBMCs?

Cellometer Auto 2000 cell counter can detect live and dead nucleated cells while excluding debris, red blood cells, platelets in your sample.

Is Automated Counting Right for You?

Our founder, Dr. Jean Qiu, developed the Cellometer Auto T4 in 2005 after receiving a request for such an instrument from a customer at NIH, and we officially launched it at AACR 2006.  As we come up on the 10 year anniversary of the original launch of our first automated cell counter it got us thinking. When we created the first automated cell counter, we created the market for such devices and we were alone in the equipment space for 2-3 years before any other company came out with competitive products. (Imitation is the highest form of flattery, right?)  It was [...]

Comparison of Trypan Blue and Fluorescence-Based Viability Detection Methods Via Morphological Observation

It's White Paper Wednesday! Read our featured white paper: Comparison of Trypan Blue and Fluorescence-Based Viability Detection Methods Via Morphological Observation Determining cell viability is a vital component in many biological experiments that range from standard cell culture to the investigation of pharmacological agents on tumor cells. One of the earliest and most common methods for measuring cell viability is the trypan blue (TB) exclusion assay [1, 2]. Over the last two decades, there have been various publications on comparing TB exclusion and fluorescence-based cellular viability assays [1, 3-5]. Previous results have shown that in a time-course measurement, TB exclusion [...]

The Historical Development of the Hemacytometer

It's White Paper Wednesday! Read our featured white paper:The Historical Development of the Hemacytometer The hemacytometer has been an essential tool for hematologists, medical practitioners, and biologists for over a century. Depending on where it is being used, the word has multiple spellings such as hemacytometer, hemocytometer, haemacytometer, or haemocytometer, but for consistency purposes the word “hemacytometer” will be used in this review. The prefix “hema”, “hemo”, “haema”, or “haemo” means blood, while “cytometer” meant a device to measure cells. The device was initially used by medical practitioners to analyze patient blood samples, which was the initial spark that created [...]

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